A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10268
Swiss-prot Accession numberP87384 (Sequence in FASTA format)
DescriptionSomatostatin 1 precursor (PSS1) [Contains: Somatostatin-14 (S-I)(SSS1)].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatostatin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSomatostatin inhibits the release of somatotropin
Protein Length115 Amino acids
Molecular weight12691
References1  PubMed abstract 8901629
2  PubMed abstract 1358069
Domain NameSomatostatin  
Hormone NameSomatostatin-14
Mature Hormone SequenceAGCKNFFWKTFTSC
Position of mature hormone in Pre-Hormone protein14 Residues from position (102-115)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10273
Swiss-prot Accession numberP87385 (Sequence in FASTA format)
DescriptionSomatostatin 2 precursor (PSS2) [Contains: [Pro2,Met13]-somatostatin-14 (S-2) (SS2)].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatostatin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionSomatostatin inhibits the release of somatotropin
Protein Length103 Amino acids
Molecular weight11648
References1  PubMed abstract 8901629
2  PubMed abstract 1358069
Domain NameSomatostatin  
Hormone Name[Pro2,Met13]-somatostatin-14
Mature Hormone SequenceAPCKNFFWKTFTMC
Position of mature hormone in Pre-Hormone protein14 Residues from position (90-103)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10664
Swiss-prot Accession numberQ09169 (Sequence in FASTA format)
DescriptionGlucagon family neuropeptides precursor [Contains: Growth hormone-releasing factor (GRF) (Growth hormone-releasing hormone) (GHRH);Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27)(PACAP27); Pituitary adenylate cyclase-activating polypeptide 38(PACAP-38) (PACAP38)].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
Function Primary role of GRF is to release GH from the pituitary
Protein Length171 Amino acids
Molecular weight19680
References1  PubMed abstract 10813784
2  PubMed abstract 1720095
Domain NameHormone_2  
Hormone NameGrowth hormone-releasing factor (GRF) (Growth hormone-releasing hormone) (GHRH)
Mature Hormone SequenceHADDLLNKAYRNLLGQLSARKYLHTLMAKHLGAVSSSLEDDSEPLS
Position of mature hormone in Pre-Hormone protein46 Residues from position (79-124)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10665
Swiss-prot Accession numberQ09169 (Sequence in FASTA format)
DescriptionGlucagon family neuropeptides precursor [Contains: Growth hormone-releasing factor (GRF) (Growth hormone-releasing hormone) (GHRH);Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27)(PACAP27); Pituitary adenylate cyclase-activating polypeptide 38(PACAP-38) (PACAP38)].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
Function PACAP plays pivotal roles as a neurotransmitter and/or a neuromodulator. Stimulates adenylate cyclase in pituitary cells
Protein Length171 Amino acids
Molecular weight19680
References1  PubMed abstract 10813784
2  PubMed abstract 1720095
Domain NameHormone_2  
Hormone NamePituitary adenylate cyclase-activating polypeptide 38
Mature Hormone SequenceHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRIKNK
Position of mature hormone in Pre-Hormone protein38 Residues from position (127-164)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10666
Swiss-prot Accession numberQ09169 (Sequence in FASTA format)
DescriptionGlucagon family neuropeptides precursor [Contains: Growth hormone-releasing factor (GRF) (Growth hormone-releasing hormone) (GHRH);Pituitary adenylate cyclase-activating polypeptide 27 (PACAP-27)(PACAP27); Pituitary adenylate cyclase-activating polypeptide 38(PACAP-38) (PACAP38)].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glucagon family.
Tissue SpecificityN/A
Post translational modification N/A
Function PACAP plays pivotal roles as a neurotransmitter and/or a neuromodulator. Stimulates adenylate cyclase in pituitary cells
Protein Length171 Amino acids
Molecular weight19680
References1  PubMed abstract 10813784
2  PubMed abstract 1720095
Domain NameHormone_2  
Hormone NamePituitary adenylate cyclase-activating polypeptide 27
Mature Hormone SequenceHSDGIFTDSYSRYRKQMAVKKYLAAVL
Position of mature hormone in Pre-Hormone protein27 Residues from position (127-153)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 6

HMRbase accession number10959
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin gamma (Gamma-MSH)
Mature Hormone SequenceYVMSHFRWNKF
Position of mature hormone in Pre-Hormone protein11 Residues from position (76-86)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10960
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameCorticotropin
Mature Hormone SequenceSYSMEHFRWGKPVGKKRRPIKVFPTDAEEESSEIFPLEL
Position of mature hormone in Pre-Hormone protein39 Residues from position (141-179)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10961
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin alpha (Alpha-MSH)
Mature Hormone SequenceSYSMEHFRWGKPV
Position of mature hormone in Pre-Hormone protein13 Residues from position (141-153)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10962
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameLipotropin beta (Beta-LPH)
Mature Hormone SequenceELSLEFDYPDTNSEEDLDDGELLDGPVKKDRKYKMHHFRWEGPPKDKRYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ
Position of mature hormone in Pre-Hormone protein79 Residues from position (182-260)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10963
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameLipotropin gamma (Gamma-LPH)
Mature Hormone SequenceELSLEFDYPDTNSEEDLDDGELLDGPVKKDRKYKMHHFRWEGPPKD
Position of mature hormone in Pre-Hormone protein46 Residues from position (182-227)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10964
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMelanotropin beta (Beta-MSH)
Mature Hormone SequenceDRKYKMHHFRWEGPPKD
Position of mature hormone in Pre-Hormone protein17 Residues from position (211-227)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10965
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameBeta-endorphin
Mature Hormone SequenceYGGFMTPERSQTPLMTLFKNAIIKNAHKKGQ
Position of mature hormone in Pre-Hormone protein31 Residues from position (230-260)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number10966
Swiss-prot Accession numberP22923 (Sequence in FASTA format)
DescriptionCorticotropin-lipotropin precursor (Pro-opiomelanocortin) (POMC)[Contains: NPP; Melanotropin gamma (Gamma-MSH); Corticotropin(Adrenocorticotropic hormone) (ACTH); Melanotropin alpha (Alpha-MSH);Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanotropin beta (Beta-MSH);Beta-endorphin; Met-enkephalin].
Source organismRana ridibunda (Laughing frog) (Marsh frog)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana;Pelophylax.
Subcellular locationN/A
Developmental StageN/A
Similarity Belongs to the POMC family.
Tissue SpecificityN/A
Post translational modification Specific enzymatic cleavages at paired basic residues yield the different active peptides.
FunctionN/A
Protein Length260 Amino acids
Molecular weight30068
References1  PubMed abstract 2260977
2  PubMed abstract 2260977
Domain NameNPP  ACTH_domain  Op_neuropeptide  
Hormone NameMet-enkephalin
Mature Hormone SequenceYGGFM
Position of mature hormone in Pre-Hormone protein5 Residues from position (230-234)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated